as far as i know, you need different headers for sure. then, cleveland heads have water passages that need to be plugged in order to be used. why use these heads on a 408? unless your porting them an doin some work it would probably be cheaper an better to get aftermarket heads. i thought of a bogus boss setup on my 302 but after talkin to my uncles who have several cleveland setups there really isnt a point with all the aftermarket heads that are made for our motors. also depends on what kinda rpm your gonna be expecting from your 408 but they would seem a little to small for your build. maybe some 4v heads would be better?