70 351C Ignition Issue?

First of All, How about that Daytona 500? Ford was 1,2 & 3 that was Awesome! OK, I have an issue that I'd like to have an answer to please. I just went through all the wiring in my ignition system and added a MSD PRO-Billet Distributor, MSD-#6201 Digital box & MSD-#8207 Coil on my 1970 351C 4v Engine. The issue I have is that if I advance the timing, the engine will start and run and detonate when I shut it off, and when a retard the timing it will be hard to start & back fire through the carb? What's up with this? Can somebody Please tell me how I can get Her right in the Middle and have No Carb Back Firing & No Detonation?
 
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What kind of condition is your timing gear set in? If the chain is worn/stretched, it will be hard to dial it in. If it's never been replaced, you should really, really plan on doing it, before valves start slapping pistons...