I have issues when I try to use CHEAP creatine. But with the BNC stuff I'm fine. I take a good bit of supplements myself. And they are working. I haven't gained much body weight but my muscle mass and build is much much better. I am 5' 10'' and 175, benching 275, squating a hair under 400 on a bar (could probably go higher if it didn't hurt my shoulder so much), and I deadlifted 405 3 times last wednesday.