No, there's just a chance the wheel won't hold air when you go to mount your tires up to them. But since they are holding fine with whats on them already they should be fine but was worth mentioning. Also if your fine with it you could always use it as a concern when discussing purchase price
Center caps wouldn't effect anything except maybe price
Thanks for the info! I think I'm going to end up buying them then. Maybe I can figure out some way to cover where the centercaps should be. I'll definitely bring up the drill holes and try to get him to lower his asking price.