I'm running about 8 lbs of boost with a 10:1 compression ratio and I have run into some problems with blown headgaskets and "blowed up" pistons. After the most recent catastrophe I finally went with some head studs rather than bolts and some of those fel-pro 1011 lockwire headgaskets, got the timing right, and it seems to be reliable now. With your higher compression, it may be tougher. If you have the time and money, I'd definitely say go ahead and swap in some pistons with a good amount of dish. Otherwise, nitrous loves high compression!