If it was big enough, you could have it off to the side. All depends on ultimate garage layout I guess.
When I was 17, I was doing electrical work with my uncle. We got a job building a brand new, multimillion dollar house in a wealthy town. The guy had the garage of my dreams. It wasn't a garage, it was a drive in basement with a 20' ceiling and you could park 20 cars easily inside it. You drove around to the back "wing" of the house, and there was a 15' garage door. There were TWO lifts (4 and 2 post) and then a walled off section for washing the cars, and then enough parking for at least a dozen cars. At the opposite end all the way inside, was a raised area that doubled as the man cave lifted about 5 feet higher than the rest of the basement. It was maybe 50 x 50 and had a bar, seating area, a projection TV and other man cave features. This "garage" was incredible, but I never got to see what was parked inside. We wrapped up the job before the moving company came in.
The only cooler basement I've ever seen is the house where a guy built a man-made pond RIGHT alongside his house, and had his side porch actually be a "dock" on the side of the house overlooking the pond. You go into the basement, and against that wall, two HUGE viewing windows with lighting under the pond water. Flip a switch at night and you could see bass and other fish swimming around. Was the coolest thing I've ever seen.