The bellhousing is the intermediary between block and transmission, with the correct one you can bolt it up to anything. With the 4 banger bellhousing I don't think it bolts to anything but a 2.3
the 300 was only ever used in trucks and industrial applications and the T5 was never seen on it I don't think. It may have the same bolt pattern as a 5.0 BUT that is a guess. Are you thinking of putting one of those in a mustang? You will want to try and adaprt it to serpentine accessories to clear the radiator, and you will need a rear sump oilpan and a revised intake or bigger hood for overhead clearance. Not sure how the motor mounts would work since it is longer than a 5.0/2.3 block. Would definitely need V8 springs, it would be more nose heavy than a 5.0.
I also have been thinking of a 300 I6 or a 250 I had a 71 maverick with a 250 with a header and a 2 barrel and it would run,I think it would be neat to see a inline 6 mustang...
They don't make great performance engines, and I'm sure you won't find many upgrades out there. But in stock form they would waste the 302 for torque.
If you want to learn more about ford inline sixes, go to http://fordsix.com . A 300 will out-torque a 302, due to the longer stroke, all things being equal. Some (including myself) have looked into putting a 300 into a fox-body, and it won't happen without some fabrication. Will it fit in the engine bay? Yes-barely. The problem is figuring out how to set up an oil pan and other associated things down below. A 250 is still going to be a little tall, but it has been done once I know of. A 200 would be the easiest, since '79-'82 Mustangs/Capris came with them stock, but you'll need the 200-specific K-member. A 250 has the same bellhousing pattern as a SBF, so that part is easy. A 200 doesn't, but you can still use a C4 or T-5. A late "big bell" 200 has 2/3's of a SBF pattern, and a SBF bell can be adapted.
on corral this guy was asking about how to put a V8 in an inline car, and had a pic of the inline6 crossmember... it has the mounts much farther forward, and looks like a 300 will bolt up to it rather easily if you fabricate a new engine-to-mount bracket.
I kinda want to do a turbo 300ci I6 one day. They are tough engines, 7 main bearings and stuff. 7,000RPM isn't out of the question, the trick is getting it to breath up there. Check out Clifford Performance for overpriced I6 parts. There was a dude selling aluminum 250ci (if I remember right) heads on ebay, they're from Australia, but are actually OEM Ford parts. Yeah, the aussies get a lot of cool stuff we never even hear about. There's a quote from some Ford US exec saying how they just blew a huge pile of cash developing the V6, and the old Ford Aus. inline 6 would beat the snot out of it.