Meaningless question. What brand and model of tire? What size? What weight wheels, front and rear? What backspacing? Did you match new shocks to the new unsprung weights? Even if you answered ALL those hypotheticals, I'd be an idiot to say I knew exactly what it would be like.
The quick answer is that "it would screw it up". The more radical you go with tire size (and the commensurate lowering of the profile that usually follows), the more tweaky or sensitive the tire is to camber change and to road smoothness. So you take a relatively well rounded (but boring) stock setup like I have on my 05, and it performs really well, but not excellent. But it does well in many conditions.
I'd be hard pressed to find a 19/20 combo, in a wide enough tire for it to look good, that would be lighter than the stock wheel/tire combo. So now you are looking at something that will, at best, perform better on a track or perfect roads, but would be horrible for daily driving in an area that has poorer roads. More weight in the rear will bring about a worsening of the live axle setup that Ford has tried so hard to optimize. New weight means that you've also upset the 3-link tuning they've done, which matches unsprung weight, shock valving and power delivery in order to produce adequate anti-squat. Will you get worse axle-hop? Maybe so. I can guess that it probably will not become a BETTER live axle setup with radically heavier wheels.
I suggest that people approach the style issue by making performance decisions first. Once you start thinking about performance first, and looks second, it turns out that there are a lot of VERY BEAUTIFUL solutions out there. They are beautiful because the technical eye looks at them and says "that's right".