Do a compression check on the engine. If it's all good, then go for it. If not, then rebuild time.
To make power naturally aspirated, you almost always have to raise the power band of the engine. Most performance head, intake, cam combos that will put you in the 300+ rwhp range will push the power band up to at least 5500-6000 RPM. For a street car, you generally won't be able to take advantage of this unless you've got the rear end geared for it and you regularly "beat" on the car. If it's a race car, then go for it. That said, the stock bottom end will likely have its life shortened.
If this is primarily a street car and the compression is good, then I would go with a 6-9psi street blower. You'll have the off-idle grunt and at least as much power, but without needing see 5000+ RPM. With good, safe, conservative tune you should be able to make 300 rwhp on pump gas and not necessarily put any undo strain on the engine.
With my combo, it feels pretty stock below 2500 RPM. It isn't until it's singing around 4000-5000 RPM that it really gets fun. Most folks with street cars like to feel that power immediately off-idle at stoplights and such,...mine...not at all. Something to think about.
Good luck with whatever decision you make.