If you are bolting up a 5.0 roller block to a C4, it's pretty easy. You have to make sure you get the correct 50-Oz flexplate and corresponding balacer. You can pick from a 3 bolt retro version or the standard 4 bolt version of those. Avoid the 1979-1985 blocks as the quality control and block lightening makes these junk.
The 1986 and newer blocks have thicker decks, thicker cylinder walls, and semi-siamesed cylinders at the bottom of the bores.