Yes, of course. The engine is an air pump: the more air you can flow/pump into it, the power you can make. That's very general and there are lots of caveats, but it is true as a very basic statement. The very first match you want to make, when you are starting with a clean sheet of paper, is what heads best suit the application. If you use the 185s and a cam something like the XE282HR, you can make about 500hp with a 393 or 408, with those heads. If you had AFR 205s, you'd make it with an XE274HR (a little less cam). To make it with a 351, you would need to step up, probably, to a solid roller with more duration, because you would be making the power at RPMs that would "challenge" most hydraulic lifters. Maybe it could be done using lightweight vavle train components, but you would pay a premium for them - more than a stroker assembly I should think.
You can have your 185s ported, but you have to take them to someone who really knows what they are doing, else they can ruin them.
Look, build a 393 using the 185s, a Victor jr. intake, an XE282HR cam (if you have a non-roller block, get the Crane retrofit roller rockers - yes they are expensive) and a 750DP carb. You will have awesome throttle response and will have trouble keeping the tires from frying. Don't get all anal about the whole thing.