If I were you I would do a 2 stage system (base/clear). It just lasts longer and looks better. DuPont, PPG, Sikkens they are all good brands. I would recomend using DuPont because they have mixing instructions on the side of the can.
As for the body work. I would use air tools ( DA and/or air file ) to do the body work. Just for the thicker parts. Always block out your filler and primer. If the car doesnt need a lot of body work and it hasnt been repainted before, then you can just sand it all w/ 320, then spray your sealer primer, then base, then clear. Make sure you take off all the moldings, lights, quarter windows etc. for a quality paint job.
Good luck. I hope it turns out the way you want.