Some more info in regard to putting the S10 T5 behind a 350 brand C in a 66 Malibu.
The S10 four cylinder, v8 Camaro, and 4.3 Astro van units have a case with a Muncie bolt pattern case. Some V6 models have Ford cases, 92 Camaro v6 for example. I got one by mistake... I have not seen a v8 Camaro or Astro van unit in either of my U Pull It yards. The trans was $75.... The Camaro unit has a 17 deg angle on the rear mount pad since its rotated in the Camaro. Makes it a pita to mount. Most likely would need a tailshaft/housing swap.
The four cylinder S10 units have an input shaft that is 1 in - 14 spline, and the shaft is about 5/8 longer than a standard Muncie. A V8 Camaro has the right input shaft length.
So, to put the S10 unit in you need an adapter (Hot Rod Works) to space the trans back so the input shaft fits. You also have to cut about 5/8 in off the input bearing retainer sleeve where the throwout bearing rides. And drill the case to bell bolt holes from 13 mm to1/2 in.
There are adapters to put the Mustang T5 into a Chevy, but you still need to swap on an S10 tailshaft and housing to get the shifter forward to clear a bench seat (in my case). So I went with the $75 junkyard S10 unit with the forward shift tower.
Next issue is S10's had electronic speedos since 88 or 89, like mine. So you cannot just install the Chevy T350 speedo driven gear and cable... There is a Cable x box to use the electronic signal to drive the mechanical speedo. Earlier S10 units had mechanical speedos but I have not found one in two years of jy searching.
S10 shift lever is way long, and has long throws. There are some aftermarket short throw shifters, and I missed one on cl last year.
The trans did barely fit the tunnel, using the stock 66 six banger powerglide crossmember moved back, with a stock T350 mount. Its tight... I do have new body bushings.
Its all doable, but a pita, much more involved than what I read/hear people doing with Fords.